Apparently a bivoltine species, flying from April to May and again from July to August. In eastern Turkey, Andrena assimilis flies from mid April to the end of May (Warncke 1974b). In Thessaly (Greece), Standfuss et al. (2011) report flight activity in April
Parasites: The bees Nomada marshamella and Nomada italica are cited as cleptoparasites of this species (Dylewska, 1987)